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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c38e9f46942476f99718a3ce91123ead6a0b4acff65693b96040a8341912a572' 
  AND token = '0JYL2C+CF08VKprNpQCfTkRh8H65fCoilCbYVg5Kz40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}