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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6842f045169bcdc2171a3c7ddafcc83c839d5a5b2a761e9020d8022900dfb97' 
  AND token = 'DillMzSbneWyIKSUrwcRDP8ru3RVxybwWt2YlvTEtqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}