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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ccb4f445242b2f65b8720096922ef3eca9a9c1d5620ede765d16c2fe4876486' 
  AND token = 'tGmyr7SkMJV8w3rATRI8r0bO4pzH2AynR5GymNjUZ3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}