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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c14c34db1865e47a890d4ad44d01b02618cbe55d38999e91a1fc4c484249ae12' 
  AND token = '4zCZlE5iXofLnHcb9rOJg1k5jM3aJOdAE9BHYXlLgcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}