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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c65a2650c134c594efeb0b4648c3129356c42cff2ee871a48b2de6aa519f16e' 
  AND token = '2kQqs3I++w/wu8a5T+LLFNYF2HAMAl3W8q5SDZ4euaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}