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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2c351d5a04fa13f7427cf0f536a687b614d402249ae55688e763a80a94ea4b' 
  AND token = 'PNcuh0YlGurTVcmvGygCmAqPi8FuKB8PNfkKP73rCY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}