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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00fe1496d6862a167629c39102d57d422600c83afb206967e6e8be28cab5b06c' 
  AND token = 'SKbPjlfdGrLwnVL00s/m5Z9EyVUsF0b4CipfrHX0rVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}