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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '771487aace2d62080e6d75d57d2ba3259d02d490432b97cabda443e3b75ecefa' 
  AND token = 'O+B0BOPk/OLt7sarGBrGm5zTkZQaM99qTYY4YgUIRjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}