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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65002f2fce2d901bb823da45882bec25d2c254f67b92b6178e525a010d4a96aa' 
  AND token = '5i7TWaweBy5+RRXRF6sbNdirPmCfvajhGkKh4b0PtyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}