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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4716ef80f8e27d72511d60618766d9e2f50849d4a850e253801bc6eb17d68c45' 
  AND token = 'ZcC18Y7Y9IlYAohkMesLJkF3fZR/dtmh1EBpX4uz8Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}