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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da819361bc83f8d6eceaef236c2e85682147fdf93a7084ec50add00076369b7' 
  AND token = 'FQPkSckK3kzl3bCCiY+muGEbusMO0XLKKS6gX25yfD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}