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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef1abd686fa136ec67786b642b57cccd40818bf2edb78408ed351c9a28103883' 
  AND token = '6xoHZ88ZrOw4O/3PpA7qr4iV0FGWesUxOHkZjfTzI4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}