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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1593d5e582e4b4fb3c9b3374587d017d4176192cf7038e04c2d0d10c02438599' 
  AND token = 'LiOKo/ow7I7gNpDx0dQMgGI3nrRYHmpFeo7Q2MmYEDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}