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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4536959e9d1ee89857c7988cf3b9b879cb97fb8222e3380e72397e2c39b731b0' 
  AND token = 'l/k5JEVfEJxIUQFW8bj/7thKpF7YVEytFBtGEBp+DMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}