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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '321f1094eb73b6bf5a36fe1e794d11ec53dfac2b0d9cd62c9904023d5bd02240' 
  AND token = 'XX2Z1+mMZxJ0n9Yg0vnB6cS5pJLWtd9+EEkRNyD7VsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}