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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72e581b110f7c378d85b5da1aa8ddaff5fa24165c8ae1ebd1622a4b413224c6d' 
  AND token = 'KtLHIxkVNsh79ZrX4NL9lnTnXdJyEDiPPShjC2h5c0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}