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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa3c4f8a8a3963656cbd2a69501c5e7995433f36029e61fb2e216f66e5b7d461' 
  AND token = 'Cn/mBCO+Jg5uxY57DuXiiFurubLdxd8OSW48YMQPFpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}