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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4fd01c0d040096ce46a5303919a8961c09190e261d86ad3a8c4e1d686bfa645' 
  AND token = 'OIZ+MfQ45C6961Ws5SbVmYX77trpofHcBiuorP+GsVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}