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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00469a517db4d20a4f1042497b6f21b57f0b8bcced4513e6299b5c9589071ea1' 
  AND token = '+oCQA/atuy7Dr+yYJbB02J0HvW7XM4HjGHaT1OhB34s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}