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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08ccd13b00bed6ac4879b1cc3542a1b1bed6b79f2b408e062fd356d180cdcf0f' 
  AND token = 'DhCghC0qb6Wx5qai4jlfEKliD8Iw4x54Y3fipU5xAUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}