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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '823af50869193cc4fbf0b029ae2e1e15b7e224c0fa68247eeb3db17fcb805ca4' 
  AND token = 'pUzJh+hRB/1Pmiqz96Yds9LaMkXAoexMHCOuEXp1jmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}