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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6883a2ccd465a1007d773423b80d95ae16c70cc3aab2ade54a3a9f492bbdb2' 
  AND token = 'NcNkIqS/6/jyVZPKvaXegwC/UsQ/5NQEfzEWqSsCMj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}