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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7839fa729142cadf57999c0b07d5db8b179c745bf371f36b6b8ab88435a3a53a' 
  AND token = 'h+3qK+AQUko+b+nbTg2Qm3pu0EN4hkirkHsNMaDx1wI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}