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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd427b27b0a0af42dbfd178aa890b1efd529b44990ffbcbae73e7428e19a3383' 
  AND token = '07hfKhg7q41n9AjBcgz5RXai1OS6QVHXAMA04br6aj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}