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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc3be2274aeb2fdb0bbff2868cdec1f21b27e86aeee61e57c5e046fbd22cab62' 
  AND token = 'UDcF2f6P6SIgvqAzYsE/eyo7YyufaLcjy8Hosju7aJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}