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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5202ef2498f72735abd792e818d51a7683295366ef4c23f83c058bcf47f9d9c2' 
  AND token = 'dYUMEryMwLHIUuTp6u9dDoVi+x7ekE61FM1yE3tRmMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}