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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4174371fafa7320d3d0c25db2bb615713fc5735521e2fa07a5f6805038990e88' 
  AND token = 'imjF17za0CuRF5fcE2+wZGK8mupSrlTbM+WeSzNfZbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}