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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605e20bf529a1a13c16b1a3ef3f0e59dc38b5040c23190c7abc78683e8e559f4' 
  AND token = 'ErMqDgmjpIy4e/R9Ew+j05Fm5d1/bwrOYr6YuhWeGXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}