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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c12f0494482df88b0d5d0f2f6f7e46211c7a5902d670f57869e2851c280c60c' 
  AND token = 'fTbrN9Fp4dmxjsLgIKph/U2YxFHMYI6cr3FucOSPUqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}