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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9892fd619c80f4c083f7aa2290b1f259497dad0d4f0b8994f7d6a081c81999fd' 
  AND token = 'FVnv/a6FNWvSj3iHvZ39UTM9wX96iLoN4Q8E0wP3EUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}