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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1857fa4c91ba3035e52118247ec076dfdc239c850f2c99f4b7de3ba3f44b9179' 
  AND token = 'nGFfkihCWC2MnOtDD4F+zN03YtKB8FM5vnCU96Y3Nyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}