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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45967f1cd29319f9fa967a756e59a43eb6acb9cf0c5f173f3f99bbd60831b6da' 
  AND token = 'i+KqXAPvFx0h6FtNZls0tMKlRZJ5fsqLUt/E84yqYSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}