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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ee725819e5fc4ad9782c985b16338b4e7783fa6976f62d1149e4acd038d9fe' 
  AND token = 'jFxGCj2/VqY0sp13YePRjnBY6AhU6442LYArmHk9tCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}