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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afe6ebe42f5ee6d123bb015751e59c7935f3286473b3b11e7d67bb877741e362' 
  AND token = 'oiLxKy9aV8Vxg+Delg3nnm2OyeMzpJJHY+sV7YQ/p7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}