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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d82e6d00504a9ddacc8771feeee70a33231b8f69c5e95b4377e8e7b0ea3e0c1' 
  AND token = 'dUd3qtY1rqb2Aa0cx1ATlQt1vZmnk1klSO2q/eAuEBM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}