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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca375fd18bd843b3eae40c9558837cf4a53cbac88ad43875fc6e21caa733e2f' 
  AND token = 'lPOqP+RxsuHe7HGEY1nfcfgNwi8+ZzPM3xm9qNI1Vbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}