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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6f2d95c96a72cd8fd22860acc1ab41adec09865602c815e5f0e9f62539e65a' 
  AND token = 'KI8Vni3JnBfQRdMkW+WeKYgVCzqAmBAV8VmwPI01r3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}