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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca27a9491d16029cc4f1842c015ee873ae6c241711a21fc1171b3070112db7f' 
  AND token = 'ZCpnXQCVW3/TMnJ6kotx0D3EGhJe2f90D7orblrZRsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}