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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ac44b92f6dc2e843dbc2998de9c718673c958c1d55d443be69451755c6eda0' 
  AND token = '5D/uRgvegcegv6bxvb5zuiFwJ9BIZs3geUPA8Q83drE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}