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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad80e6693efafe79c65fde7fdaf3796ff96258f06d106f4b7d2f26c06ace2eda' 
  AND token = 'r1T5YQ7yln/eNImjHVVHQs7z2+qj8sJYc/Vu6EIMBfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}