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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c95c9385855d0cefb8321d3e5cfed21d18b4be2d99d34a610db27d1180d7d5b2' 
  AND token = 'wkU5wHPemMkU3B3bSlso1vbpXyZOWIVuzWv6TfobIk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}