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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1846fd9a7bab88a2f5f1bbf62831176108f467f208af4d96fecf2904f2f912b' 
  AND token = 'COcs8ITZAeXeMTQBfWg/6wiBEtTWkZsLOMLRKPdHoxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}