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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1fd00b1ead22f1e3aab5dc1274d93e1f5249300f0f38a488da999aac975f284' 
  AND token = 'XwLFUJxk/ZgC4qmG/pYRAn5koom5JCgNMyk3y/xerSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}