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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ffc033a8eddc526d467ca9f7c6c18db675cd864eb44815124f398254ed7637b' 
  AND token = 'Pxt4INTKHfuuWTmtL6PpOz9og4TxTTBpV98hbU4pbGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}