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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a7a77102f3a8eb8c4bbaecbe62d4697803cc72445e2d19db62c46dc9210e637' 
  AND token = 'e75Y+MTpC4Ey32xslFP7t/GQm9kh3uuWOJgDnxtXbGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}