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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9bdf2e7deec39feb5abd9849b39aefd4ad2cb8f35c99d994115ebfc4b168293' 
  AND token = 'hza346tdZ4DR2N1lbES/nzLrc0s0ySSB7wZznDVucDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}