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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9536d532bcb8f547f1d929e631b78b53a5f170ca5c7c7d059e921146f33fa6ef' 
  AND token = 'OoQ/dJN0hsNXKcFze7iWWMpwD4xyEix47Co6KH/jqL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}