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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6ab5d28732f8e0abcd384ebda6efc077d5fc9d256adc2a5d3b699d8d0418c1' 
  AND token = 'WtJAa9GGNMifr3esMorGZGBe5AXI5UrS7he9NivaalY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}