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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3fea50c900e7a0f07984620cd0046823e5ca6b6c15af0cc7356f75337f3258' 
  AND token = 'd1GlQjhJAA0OE1WoEzvflzPWwwdlKsE85xgH1MyPdyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}