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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd05d1999d50241be35354572589b2f09fb84e114e32d91f7a7910f505d3e7a38' 
  AND token = 'QBdArhScTEghwEoLeNfIxeu/VB8H8vwpPdHGxv8v1lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}